My fascination with chemical instrumentation, especially mass spectrometry (MS), has remained persistent throughout my scientific career, and my postdoctoral work has sharpened my vision for MS innovations through the lens of needs within the glycoscience community. In my graduate work with Prof. Josh Coon at the University of Wisconsin-Madison, I developed MS technology for proteomic applications, with an emphasis on a tandem MS method co-invented by Prof. Coon called electron transfer dissociation (ETD). I built custom instrumentation, methodology, and software to implement supplemental activation strategies (termed activated ion-ETD, AI-ETD) to improve ETD-based fragmentation across bottom-up and top-down proteomics, and my graduate work continues to impact research and MS instrument development efforts for peptide, protein, and post-translational modification analyses. My graduate research efforts culminated in large-scale N-glycoproteome characterization with AI-ETD, which opened my eyes to the world of glycobiology – where I saw opportunity and intrigue. My postdoctoral research with Prof. Carolyn Bertozzi, known for her transformative work in chemical glycoscience, has crystallized my commitment to interdisciplinary science that uses chemical tools to explore fundamental questions in biology. Here, I have focused on two areas ripe for discovery within glycoscience, yet in need of new technology: mucin-domain glycoproteins and the secretome. As an incoming Assistant Professor in the Department of Chemistry at the University of Washington, I am now excited to devote my career to studying fundamental roles of glycosylation in cell surface biology through creative technology development.